iSeekGolf writers Rod Morri, Henry Peters and Bruce Young offer their predictions on who is likely to win, contend and surprise.
For the Win: So Yeon Ryu.
You don't fluke your way to World Number One and she has been the player to beat almost every week of 2017. She seemed a little uncomfortable in her first start as the world's top ranked player at the KPMG Women's PGA but there will be none of that this week.
Top-5: Minjee Lee.
The Western Australian will have been less than pleased with her play at Olympia Fields and looking to make amends this week. This event favours the players who are sound in all departments of the game and Lee is unquestionably in that group. If not for Ryu, she might have been my favourite.
Sleeper: Angel Yin.
The young American has talent to burn and will be the next teen to enter the tussle at the top of the world rankings. She's aggressive, confident, makes birdies in bunches and isn't afraid of the big stage. Some of that may work against her this week on a USGA set-up but, if things go her way, she could be a contender.
For the Win: Lexi Thompson
Hard to look past So Yeon Ryu, but Lexi Thompson's play this season has been sublime. If it weren't for her penalty at the ANA Inspiration - which she rightly deserved - it would be hard imagine a better start to a season. The American's level of motivation to atone for the ANA couldn't be higher, and at second only to Ryu on the money list, her game is ready.
Top-5: Minjee Lee
The young Australian has been a model of consistency in 2017 with 6 top-10s including a 3rd at the year's first major. She's been threatening to break through at the majors for a while and - as a 3-time LPGA Tour winner, appears ready to do so. Her absence of a top-20 finish at the Women's US Open is only a minor concern because she's put herself in winning positions more than but a handful this season.
Sleeper: Carlota Ciganda
The 27-year-old Spaniard took longer than some may have expected to make a name for herslf on the LPGA but did it with a bang with two victories late last year. In her early 20s, she had the look of a future star, topping the Ladies European Tour money list in her rookie pro season in 2012. She's had a relatively modest three top-10s this year but a 20th at the Women's PGA and a 10th place finish the week before in Arkansas show she may be a value propostion.
For the Win: So Yeon Ryu.
A former winner and great US Women's Open record. Arguably in the best form of her life right now. Leads world ranking, money list and Race to the CME Globe in 2017. Logical favourite.
Top-5: Amy Yang.
The South Korean owns one of the great records in this event despite not winning. Threw out encouraging signals with a runner-up finish in Arkansas and a 4th place finish at the KPMG Women's PGA.
Sleeper: Michelle Wie.
The 2014 winner has found a rich vein of form in 2017 recording four top-4 finishes in her last six starts. Despite that win three years ago, her overall US Open record is not great but there is something about Wie's game right now to suggest this year could be different.